Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy has been shown to offer fast and efficient reperfusion with high recanalization rates. However, due to the inherent risks of thrombectomy, indications including evidence of good collateral circulation should be present. Currently, methods for evaluating collateral circulation are limited. We are working on developing automated techniques to compute a collateral circulation score based on differences seen in mean intensities between left and right cerebral hemispheres in 4D angiography images.
- Xiao Y, Alamer A, Fonov V, Lo BWY, Tampieri D, Collins DL, Rivaz H, Kersten-Oertel M. Towards automatic collateral circulation score evaluation in ischemic stroke using image decompositions and support vector machines. In: Cardoso M. et al. (eds) Molecular Imaging, Reconstruction and Analysis of Moving Body Organs, and Stroke Imaging and Treatment. CMMI 2017, SWITCH 2017, RAMBO 2017. Lecture Notes in Computer Science, vol 10555. Springer, Cham.
- Kersten-Oertel, M., Alamer, A., Fonov, V., Lo, B. W., Tampieri, D., & Collins, D. L. (2020). Towards a Computed Collateral Circulation Score in Ischemic Stroke. arXiv preprint arXiv:2001.07169.